Estimation of theRNU2macrosatellite mutation rate byBRCA1mutation tracing
نویسندگان
چکیده
منابع مشابه
Estimation of the RNU2 macrosatellite mutation rate by BRCA1 mutation tracing
Large tandem repeat sequences have been poorly investigated as severe technical limitations and their frequent absence from the genome reference hinder their analysis. Extensive allelotyping of this class of variation has not been possible until now and their mutational dynamics are still poorly known. In order to estimate the mutation rate of a macrosatellite, we analysed in detail the RNU2 lo...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2014
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/gku639